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Inspiration and the Bible

In 2 Timothy 3:16, the apostle Paul writes: "All Scripture is given by inspiration of God." Two questions arise: 1) What is meant by inspiration?; and 2) How may we know that the Bible is inspired?

1) What is meant by inspiration? First, as Warfield has pointed out, "God breathed out" (theopneustos) is a better translation of the original language than "inspired." Theopneustos actually speaks of the fact that the Scripture is "breathed out" of the mouth of God, whereas "inspired" means "breathed in."