The first public services of River Valley Reformed Presbyterian Mission (RPCUS) were held on the Lord's Day, April 20th, 2003. There were 18 people on hand (including one visitor) as mission worker Mark Anthony began teaching through the first epistle of John.

The River Valley Reformed Presbyterian Mission officially became a new work of the Reformed Presbyterian Church in the United States (RPCUS) at the 2003 Stated Meeting of Covenant Presbytery.